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PapersPMID:28078249

Effects of Urtica dioica supplementation on blood lipids, hepatic enzymes and nitric oxide levels in type 2 diabetic patients: A double blind, randomized clinical trial.

Avicenna journal of phytomedicine2016The record ↗

findings
2
compound
1
endpoints
2
  1. Finding, moderate evidencelowersAlanine aminotransferase
  2. Finding, moderate evidenceraisesSuperoxide dismutase activity
Study, every finding
RCT · 8 weeks
Dose studied, every finding
5 mL three times a day, after each main meal, for 8 weeks
Population, every finding
Women over 50 with type 2 diabetes taking metformin and glibenclamide in both arms; 48 completed the trial (24 nettle, 24 placebo)
  • “Patients undergoing post-treatment with U. dioica extract showed significant decrease (p<0.001) in SGPT after 8 weeks as compared to patients undergoing pre-treatment with U. dioica extract and patients using placebo.”
    Interests
    Industry funded
  • “The result showed that extract of U. dioica increased SOD in the patients undergoing 8 weeks of post-treatment as compared to patients undergoing pre-treatment with U. dioica extract at the beginning of the study and the placebo group.”
    Interests
    Industry funded

Study record

Design
randomised controlled trial
Species
human
Population
50 women with type 2 diabetes on metformin and glibenclamide, Shahroud, Iran
Participants
50
Comparator
placebo
Duration
56 days
Endpoints measured
14