Papers/PMID:28074795
Comparative effect of grape seed extract (Vitis vinifera) and ascorbic acid in oxidative stress induced by on-pump coronary artery bypass surgery.
Annals of cardiac anaesthesia2017The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
L-ascorbic acid — increases total antioxidant capacity
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Finding“TAC was significantly higher (P < 0.05) in both GSE and Vitamin C groups comparing control group at T2 and T3 times.”
Quoted verbatim from Comparative effect of grape seed extract (Vitis vinifera) and ascorbic acid in oxidative stress induced by on-pump coronary artery bypass surgery.. - Study
- RCT
- Dose
- 25 mg/kg vitamin C through pump circulation during surgery
- Population
- Patients undergoing elective first-time coronary artery bypass surgery on cardiopulmonary bypass; vitamin C arm versus a no-treatment control arm (a separate grape seed extract arm was also run); coronary sinus blood at ischemia (T2) and reperfusion (T3)
Comparative effect of grape seed extract (Vitis vinifera) and ascorbic acid in oxidative stress induced by on-pump coronary artery bypass surgery.2017PMID:28074795Permalink