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PapersPMID:26630290

Euterpe oleracea Mart.-Derived Polyphenols Protect Mice from Diet-Induced Obesity and Fatty Liver by Regulating Hepatic Lipogenesis and Cholesterol Excretion.

PloS one2015The record ↗

  1. Finding, very limited evidencelowersSerum leptin

What moved

1 findingHow to read these marks →
  • Decreases serum leptin

    very limited

    “Treatment with ASE reduced plasma leptin levels in HF mice (p<0.05), indicating restoration of leptin sensitivity.”
    Study
    animal · not in humans
    Duration
    3 months
    Dose studied
    300 mg/kg/day by intragastric gavage for 12 weeks
    Population
    Male C57BL/6 mice fed a 60% fat diet in both arms; açaí seed extract versus no extract, 12 weeks, after a 6 hour fast

Study record

Design
animal study, in vivo
Species
animal
Population
Male C57BL/6 mice, 5 weeks old at allocation, fed a standard diet (10% fat) or a high-fat diet (60% fat) to induce obesity and hepatic steatosis
Participants
not reported
Comparator
no treatment
Duration
84 days
Endpoints measured
26