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PapersPMID:26134625

Antinociceptive effects of hydroalcoholic extract from Euterpe oleracea Mart. (Açaí) in a rodent model of acute and neuropathic pain.

BMC complementary and alternative medicine2015The record ↗

  1. Finding, insufficient evidencelowersFormalin-test nociceptive behaviour time

What moved

1 findingHow to read these marks →
  • Decreases formalin-test nociceptive behaviour time

    insufficient

    “Reactivity in the inflammatory phase was reduced by acetylsalicylic acid to 101.9 ± 14.9 s and by (30, 100, or 300 mg.kg−1 ASE) to 122.5 ± 14.5 s, 90.1 ± 15.2 s and 106.4 ± 11.0 s, respectively (p < 0.05).”
    Study
    animal · not in humans
    Dose studied
    30, 100 or 300 mg/kg orally, single dose 15 min before formalin
    Population
    Male Swiss mice; late (inflammatory) phase, 15-30 min after intraplantar formalin; all three ASE doses (30, 100, 300 mg/kg) reduced licking and biting time versus saline

Study record

Design
animal study, in vivo
Species
animal
Population
Male Swiss mice (18-25 g) in acute and inflammatory pain models; male Wistar rats (180-220 g) with spinal nerve ligation neuropathic pain
Participants
not reported
Comparator
placebo
Duration
7 days
Endpoints measured
32