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Catalyst

PapersPMID:25686270

Ganoderma lucidum mushroom for the treatment of cardiovascular risk factors.

The Cochrane database of systematic reviews2015The record ↗

findings
4
compound
1
endpoints
4
PMID:25686270
  1. Finding, very limited evidenceno difference foundGlycated haemoglobin (HbA1c)
  2. Finding, very limited evidenceno difference foundLDL cholesterol
  3. Finding, very limited evidenceno difference foundBody mass index
  4. Finding, very limited evidenceno difference foundTotal cholesterol (TC)
Study, every finding
meta-analysis
Dose studied, every finding
1.4 g to 3 g per day
Population, every finding
Adults with type 2 diabetes mellitus; pooled from two placebo-controlled trials

No finding here moved its endpoint.

  • “Results from two studies showed that G lucidum was not associated with statistically or clinically significant reduction in HbA1c (WMD -0.10%; 95% CI -1.05% to 0.85%; 130 participants), total cholesterol (WMD -0.07mmol/L; 95% CI -0.57 mmol/L to 0.42 mmol/L; 107 participants ), low-density lipoprotein cholesterol (WMD 0.02 mmol/L; 95% CI -0.41 mmol/L to 0.45 mmol/L; 107 participants), or body-mass index (WMD -0.32 kg/m(2); 95% CI -2.67 kg/m(2) to 2.03 kg/m(2;) 107 participants).”

Study record

Design
meta-analysis
Species
human
Population
Adults with type 2 diabetes mellitus (three studies used for statistical analyses); Ganoderma lucidum for cardiovascular risk factors
Participants
398
Comparator
placebo
Duration
not reported
Endpoints measured
10