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Catalyst

PapersPMID:25074771

Effects of a lutein supplement on the plasma lutein concentration and macular pigment in patients with central serous chorioretinopathy.

Investigative ophthalmology & visual science2014The record ↗

  1. Finding, very limited evidenceno difference foundMacular pigment optical density

No finding here moved its endpoint.

What did not

1 findingHow to read these marks →
  • No detected effect on macular pigment optical density

    very limited

    “The plasma concentration in the lutein group was significantly higher than in controls at 1 and 4 months (P < 0.0001 for both comparisons); however, the MPOD values did not differ significantly between groups at 1 (P = 0.479) or 4 months (P = 0.883).”
    Study
    RCT
    Dose studied
    lutein 20 mg/d versus placebo
    Population
    patients with central serous chorioretinopathy; MPOD by autofluorescence spectrometry; null at both 1 and 4 months

Study record

Design
randomised controlled trial
Species
human
Population
patients with central serous chorioretinopathy
Participants
39
Comparator
placebo
Duration
122 days
Endpoints measured
11