PapersPMID:24120618
Effects of a nitrate-rich meal on arterial stiffness and blood pressure in healthy volunteers.
- findings
- 4
- compound
- 1
- endpoints
- 4
- no difference found
- 3
- Study, every finding
- crossover · 26 participants
- Dose studied, every finding
- single meal containing 220 mg nitrate derived from spinach, 2000 kJ
- Population, every finding
- healthy men and women aged 38-69 years; acute effect up to 210 min after a single energy-matched 2000 kJ meal, high-nitrate spinach meal against low-nitrate control meal
What moved
How to read these marks →- Decreases systolic blood pressure
very limited
“Spinach compared with control resulted in higher large artery elasticity index (P<0.001), and lower pulse pressure (P<0.001) and systolic blood pressure (P<0.001).”
What did not
“Post meal carotid-femoral pulse wave velocity (P=0.07), augmentation index (P=0.63), small artery elasticity index (P=0.98) and diastolic blood pressure (P=0.13) were not significantly altered by spinach relative to control.”
- No detected effect on diastolic blood pressure
very limited
- No detected effect on augmentation index
very limited
Study record
- Design
- crossover trial
- Species
- human
- Population
- healthy men and women aged 38-69 years; two energy-matched (2000kJ) meals in random order, high nitrate (spinach) versus low nitrate control
- Participants
- 26
- Comparator
- placebo
- Duration
- not reported
- Endpoints measured
- 9