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Catalyst

PapersPMID:23737086

Tyrosine supplementation for phenylketonuria.

The Cochrane database of systematic reviews2013The record ↗

  1. Finding, very limited evidenceraisesBlood tyrosine concentration

What moved

1 findingHow to read these marks →
  • Increases blood tyrosine concentration

    very limitedreplicated ×2

    “The blood tyrosine concentrations were significantly higher in the participants receiving tyrosine supplements than those in the placebo group, mean difference 23.46 (95% confidence interval 12.87 to 34.05).”
    Study
    meta-analysis
    Effect
    23.46 mean difference, 95% CI 12.87 to 34.05
    Population
    People with phenylketonuria receiving tyrosine supplementation alongside or instead of a phenylalanine-restricted diet, versus placebo; pooled randomised or quasi-randomised trials

Study record

Design
meta-analysis
Species
human
Population
People with phenylketonuria on or off a phenylalanine-restricted diet
Participants
56
Comparator
placebo
Duration
not reported
Endpoints measured
2
Declined
this platform holds no node for the endpoint