Papers/PMID:22377763
Association of vitamin A and carotenoid intake with melanoma risk in a large prospective cohort.
The Journal of investigative dermatology2012The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
all-trans-retinol — decreases melanoma incidence
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Findingreplicated ×1“Relative to non-use, current (HR 0.60, 95% CI: 0.41–0.89) but not former (HR 0.90, 95% CI: 0.57–1.43) use of individual retinol supplements at baseline was associated with a decreased risk of melanoma.”
Quoted verbatim from Association of vitamin A and carotenoid intake with melanoma risk in a large prospective cohort.. - Study
- cohort
- Population
- Men and women aged 50-76 years in the VITAL cohort, western Washington; current users of individual retinol supplements at baseline compared with non-users; incident melanoma by SEER linkage to 2007
Effect 0.6 hazard ratio, 95% CI 0.41 to 0.89
Association of vitamin A and carotenoid intake with melanoma risk in a large prospective cohort.2012PMID:22377763Permalink