PapersPMID:22055504
Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans.
- findings
- 4
- compound
- 1
- endpoints
- 4
- no difference found
- 2
resveratrol- Study, every finding
- crossover · 4 weeks
- Dose studied, every finding
- 150 mg/day resVida (99% resveratrol) for 30 days
- Population, every finding
- 11 obese but otherwise healthy men in a randomised double-blind crossover trial with a four-week wash-out
What moved
How to read these marks →- Decreases systolic blood pressure
limitedreplicated ×2
“Resveratrol significantly lowered systolic blood pressure by ~5 mmHg, while resveratrol had no effect on diastolic blood pressure (table 3).”
- Interests
- Industry funded
- Decreases triglycerides
very limitedreplicated ×2
“Plasma triglyceride concentrations were significantly lower after resveratrol compared to placebo.”
- Interests
- Industry funded
What did not
- No detected effect on body mass
limitedreplicated ×2
“Although calorie restriction causes metabolic adaptations also partly through weight loss, we found no effect on body mass (99.9 ± 3.9 vs. 99.6 ± 2.5 kg, in resveratrol vs. placebo, p=0.43).”
- Interests
- Industry funded
- No detected effect on diastolic blood pressure
limitedreplicated ×2
- Interests
- Industry funded
Study record
- Design
- crossover trial
- Species
- human
- Population
- Obese but otherwise healthy male volunteers; resveratrol (resVida) versus placebo in a randomized double-blind crossover design
- Participants
- 11
- Comparator
- placebo
- Duration
- 30 days
- Endpoints measured
- 58