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PapersPMID:20447305

Safety and Efficacy of Dietary Agmatine Sulfate in Lumbar Disc-associated Radiculopathy. An Open-label, Dose-escalating Study Followed by a Randomized, Double-blind, Placebo-controlled Trial.

Pain medicine (Malden, Mass.)2010The record ↗

  1. Finding, very limited evidenceraisesHealth-related quality of life

What moved

1 findingHow to read these marks →
  • “Expressed as percent of baseline values, significantly enhanced improvement in average pain measures and in quality of life scores occurred after treatment in the agmatine group (26.7% and 70.8%, respectively) as compared with placebo (6.0% [P </= 0.05] and 20.0% [P </= 0.05], respectively).”
    Study
    RCT
    Duration
    14 days
    Dose studied
    agmatine sulfate 2.670 g/day for 14 days
    Population
    Adults with herniated lumbar disc-associated radiculopathy, randomised double-blind to agmatine sulfate or placebo; analysed n = 31 agmatine and 30 placebo; abstract only

Study record

Design
randomised controlled trial
Species
human
Population
Participants diagnosed with herniated lumbar disc-associated radiculopathy
Participants
not reported
Comparator
placebo
Duration
14 days
Endpoints measured
2