Papers/PMID:16112685
Inhibitory mechanisms of highly purified vitamin B2 on the productions of proinflammatory cytokine and NO in endotoxin-induced shock in mice.
Life sciences2005The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
riboflavin — decreases interleukin-6 concentration
InsufficientEvidence strength: insufficient. Mechanistic inference, no evidence found, or evidence weakened below very limited.Finding“Vitamin B2 at 20 mg/kg (protective effect on mice mortality induced by LPS), intravenously administered 6 h after LPS injection, significantly decreased the plasma elevated levels of IL-6 and MIP-2 at 9 and 12 h.”
Quoted verbatim from Inhibitory mechanisms of highly purified vitamin B2 on the productions of proinflammatory cytokine and NO in endotoxin-induced shock in mice.. - Study
- animal · not in humans
- Dose
- 20 mg/kg intravenously, 6 h after LPS
- Population
- Mice with LPS-induced endotoxic shock; treatment given 6 h after LPS injection; plasma IL-6 at 9 and 12 h
Inhibitory mechanisms of highly purified vitamin B2 on the productions of proinflammatory cytokine and NO in endotoxin-induced shock in mice.2005PMID:16112685Permalink