Papers/PMID:14724051
5-Hydroxy-L-tryptophan suppresses food intake in food-deprived and stressed rats.
Pharmacology, biochemistry, and behavior2004The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
5-hydroxy-L-tryptophan — increases plasma/serum 5-hydroxytryptophan concentration
InsufficientEvidence strength: insufficient. Mechanistic inference, no evidence found, or evidence weakened below very limited.Findingreplicated ×1“Additionally, among humans, oral 5-HTP (1.2-2.0 mg/kg) produced, after 1 and 2 h, a significant increase in plasma 5-HTP (1.5- to 2.3-fold).”
Quoted verbatim from 5-Hydroxy-L-tryptophan suppresses food intake in food-deprived and stressed rats.. - Study
- case series
- Dose
- oral 5-HTP 1.2-2.0 mg/kg, single dose
- Population
- human volunteers given a single oral dose of 5-HTP (a secondary human sub-study within an otherwise rat food-intake paper)
5-Hydroxy-L-tryptophan suppresses food intake in food-deprived and stressed rats.2004PMID:14724051Permalink