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PapersPMID:10722036

Reduction of resuscitation fluid volumes in severely burned patients using ascorbic acid administration: a randomized, prospective study.

Archives of surgery (Chicago, Ill.2000The record ↗

  1. Finding, very limited evidencelowersMalondialdehyde (circulating)

What moved

1 findingHow to read these marks →
  • “Serum malondialdehyde levels were lower in the ascorbic acid group at 18, 24, and 36 hours after injury (P<.05).”
    Study
    RCT
    Dose studied
    ascorbic acid infused during the initial 24-hour study period
    Population
    Severely burned patients (burns over more than 30% of total body surface area) hospitalized within 2 hours of injury; both arms received Ringer lactate fluid resuscitation, control arm no ascorbic acid

Study record

Design
randomised controlled trial
Species
human
Population
Severely burned patients (burns over more than 30% TBSA) hospitalized within 2 hours after injury
Participants
37
Comparator
no treatment
Duration
not reported
Endpoints measured
7