Reactions
PTGS2
59 reactions
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + proton + NADPH(4-) + dioxygen → MAM00374c + water + NADP(3-)
→ Balanced · EC 1.14.99.1
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + proton + NADPH(4-) + dioxygen → MAM00374x + water + NADP(3-)
→ Balanced · EC 1.14.99.1
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + proton + NADPH(4-) + dioxygen → MAM00374r + water + NADP(3-)
→ Balanced · EC 1.14.99.1
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2 dioxygen → prostaglandin G2
→ Balanced · EC 1.14.99.1
- 2 proton + prostaglandin G2 → water + prostaglandin H2
→ Unbalanced · EC 1.14.99.1
- 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + dioxygen → MAM00322c
→ Balanced · EC 1.14.99.1
- (8Z,11Z,14Z)-eicosatrienoate + 2 dioxygen → MAM02791c
→ Balanced · EC 1.14.99.1
- (8Z,11Z,14Z)-eicosatrienoate + 2 dioxygen → MAM02791r
→ Balanced · EC 1.14.99.1
- 2 proton + MAM02791c ⇌ water + prostaglandin H1
⇌ Unbalanced · EC 1.14.99.1
- 2 proton + MAM02791r ⇌ water + prostaglandin H1
⇌ Unbalanced · EC 1.14.99.1
- (9S)-hydroperoxy-(10E,12Z)-octadecadienoate + proton + NADPH(4-) ⇌ 9-hydroxy-(10E,12Z)-octadecadienoate + water + NADP(3-)
⇌ Balanced · EC 1.14.99.1
- (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + dioxygen → MAM00375c
→ Balanced · EC 1.14.99.1
- (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + dioxygen → MAM00375n
→ Balanced · EC 1.14.99.1
- (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + dioxygen → MAM00375r
→ Balanced · EC 1.14.99.1
- (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + dioxygen → MAM00375x
→ Balanced · EC 1.14.99.1
- (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + proton + NADPH(4-) + 2 dioxygen → water + NADP(3-) + MAM02716c
→ Balanced · EC 1.14.99.1
- (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + proton + NADPH(4-) + 2 dioxygen → water + NADP(3-) + MAM02716n
→ Balanced · EC 1.14.99.1
- (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + proton + NADPH(4-) + dioxygen → (18R)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + water + NADP(3-)
→ Balanced · EC 1.14.99.1
- 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + dioxygen → MAM00322r
→ Balanced · EC 1.14.99.1
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + proton + NADPH(4-) + 2 dioxygen → water + NADP(3-) + prostaglandin H2
→ Balanced · EC 1.14.99.1
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + proton + NADPH(4-) + 2 dioxygen → water + NADP(3-) + prostaglandin H2
→ Balanced · EC 1.14.99.1
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + 2 dioxygen → prostaglandin H2 + A + water
→ Balanced
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + dioxygen → 11R-hydroperoxy-(5Z,8Z,12E,14Z)-eicosatetraenoate
→ Balanced
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + dioxygen → (15R)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate
→ Balanced
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2 dioxygen → prostaglandin G2
→ Balanced
- prostaglandin G2 + AH2 → prostaglandin H2 + A + water
→ Balanced
- 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 2 dioxygen → 2-glyceryl-prostaglandin G2
→ Balanced
- 2-glyceryl-prostaglandin G2 + AH2 → 2-glyceryl-prostaglandin H2 + A + water
→ Balanced
- (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + AH2 + dioxygen → (5S,11R)-dihydroxy-(6E,8Z,12E,14Z)-eicosatetraenoate + A + water
→ Balanced
- (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + AH2 + dioxygen → (5S,15S)-dihydroxy-(6E,8Z,11Z,13E)-eicosatetraenoate + A + water
→ Balanced
- (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + AH2 + dioxygen → (5S,15R)-dihydroxy-(6E,8Z,11Z,13E)-eicosatetraenoate + A + water
→ Balanced
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid + AH2 + dioxygen → 17R-hydroxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate + A + water
→ Balanced
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid + AH2 + dioxygen → 13-hydroxy-(4Z,7Z,10Z,14E,16Z,19Z)-docosahexaenoate + A + water
→ Balanced
- (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + dioxygen → (18R)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + A + water
→ Balanced
- (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + dioxygen → (15R)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + A + water
→ Balanced
- (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + AH2 + dioxygen → 13R-hydroxy-(7Z,10Z,14E,16Z,19Z)-docosapentaenoate + A + water
→ Balanced
- (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + AH2 → (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + A + water
→ Balanced
- (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + dioxygen → (15S)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + A + water
→ Balanced
- (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + dioxygen → (18S)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + A + water
→ Balanced
- (8Z,11Z,14Z)-eicosatrienoate + 2 dioxygen → prostaglandin G1
→ Balanced
- prostaglandin G1 + AH2 → prostaglandin H1 + A + water
→ Balanced
- (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + 2 dioxygen → prostaglandin G3
→ Balanced
- prostaglandin G3 + AH2 → prostaglandin H3 + A + water
→ Balanced
- (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + dioxygen → (11R)-hydroxy-(5Z,8Z,12E,14Z,17Z)-eicosapentaenoate + A + water
→ Balanced
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + dioxygen → (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + A + water
→ Balanced
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + dioxygen → (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + A + water
→ Balanced
- (9Z,12Z)-octadecadienoate + AH2 + dioxygen → 13-hydroxy-(9Z,11E)-octadecadienoate + A + water
→ Balanced
- (9Z,12Z)-octadecadienoate + AH2 + dioxygen → 9-hydroxy-(10E,12Z)-octadecadienoate + A + water
→ Balanced
- 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + dioxygen → 2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + water
→ Balanced
- 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + dioxygen → 2-[(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + water
→ Balanced