Reactions
CYP2C9
131 reactions
- proton + NADPH(4-) + 2 dioxygen + MAM03911r → hydrogen peroxide + NADP(3-) + MAM03914r
→ Balanced · EC 1.14.13.-, 1.14.14.1
- proton + NADPH(4-) + dioxygen + MAM04000r → water + NADP(3-) + MAM04001r
→ Balanced · EC 1.14.13.-
- dioxygen + MAM04001r → proton + water + MAM04003r
→ Balanced · EC 1.14.13.-
- an organic molecule + reduced [NADPH--hemoprotein reductase] + dioxygen ⇌ an alcohol + oxidized [NADPH--hemoprotein reductase] + water + hydron
⇌ Balance undeterminable
- CHEBI:15383 + reduced [NADPH--hemoprotein reductase] + dioxygen ? CHEBI:15389 + oxidized [NADPH--hemoprotein reductase] + water + hydron
? Balance undeterminable
- CHEBI:15382 + reduced [NADPH--hemoprotein reductase] + dioxygen ? CHEBI:15388 + oxidized [NADPH--hemoprotein reductase] + water + hydron
? Balance undeterminable
- CHEBI:15383 + reduced [NADPH--hemoprotein reductase] + dioxygen ? CHEBI:10782 + oxidized [NADPH--hemoprotein reductase] + water + hydron
? Balance undeterminable
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + dioxygen → 19-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable
- (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + reduced [NADPH--hemoprotein reductase] + dioxygen → (17R,18S)-epoxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable
- estrone + reduced [NADPH--hemoprotein reductase] + dioxygen → 2-hydroxyestrone + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable
- 17beta-estradiol + reduced [NADPH--hemoprotein reductase] + dioxygen → 2-hydroxy-17beta-estradiol + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + dioxygen → (14S,15R)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + dioxygen → (14R,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + dioxygen → (11S,12R)-epoxy-(5Z,8Z,14Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + dioxygen → (11R,12S)-epoxy-(5Z,8Z,14Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + dioxygen → (8R,9S)-epoxy-(5Z,11Z,14Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + dioxygen → (8S,9R)-epoxy-(5Z,11Z,14Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable
- cholesterol + reduced [NADPH--hemoprotein reductase] + dioxygen → 25-hydroxycholesterol + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + dioxygen → 14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + dioxygen → 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable
- (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + reduced [NADPH--hemoprotein reductase] + dioxygen → 8,9-epoxy-(5Z,11Z,14Z,17Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable
- (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + reduced [NADPH--hemoprotein reductase] + dioxygen → 11,12-epoxy-(5Z,8Z,14Z,17Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable
- (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + reduced [NADPH--hemoprotein reductase] + dioxygen → 14,15-epoxy-(5Z,8Z,11Z,17Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + dioxygen → 13-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + dioxygen → 10-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + dioxygen → (12R)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + dioxygen → (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + dioxygen → (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable
- (9Z,12Z)-octadecadienoate + reduced [NADPH--hemoprotein reductase] + dioxygen → (13R)-hydroxy-(9Z,11E)-octadecadienoate + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable
- (9Z,12Z)-octadecadienoate + reduced [NADPH--hemoprotein reductase] + dioxygen → (9R)-hydroxy-(10E,12Z)-octadecadienoate + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + dioxygen → 13(S)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + water + hydron
→ Balance undeterminable