Reactions
ALOX5
46 reactions
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + dioxygen → 5(S)-HPETE
→ Balanced · EC 1.13.11.34
- 5(S)-HPETE → water + leukotriene A4
→ Balanced · EC 1.13.11.34
- 5(S)-HETE + 2 proton + dioxygen → MAM01050c + water
→ Unbalanced · EC 1.13.11.34
- MAM00374c + dioxygen → MAM00098c + water
→ Balanced · EC 1.13.11.34
- MAM00374x + dioxygen → MAM00098x + water
→ Balanced · EC 1.13.11.34
- MAM00374r + dioxygen → MAM00098r + water
→ Balanced · EC 1.13.11.34
- MAM00365c + 2 proton + dioxygen → water + MAM02396c
→ Unbalanced · EC 1.13.11.34
- MAM00365n + 2 proton + dioxygen → water + MAM02396n
→ Unbalanced · EC 1.13.11.34
- 15(S)-HPETE + dioxygen → MAM01058c + hydrogen peroxide
→ Balanced · EC 1.13.11.34
- 15(S)-HPETE + dioxygen → MAM01058n + hydrogen peroxide
→ Balanced · EC 1.13.11.34
- 15(S)-HPETE + dioxygen → MAM01058r + hydrogen peroxide
→ Balanced · EC 1.13.11.34
- 15(S)-HPETE + FAD → MAM01058x + FADH2
→ Balanced · EC 1.13.11.34
- MAM00307c + 2 proton + dioxygen → water + MAM02364c
→ Unbalanced · EC 1.13.11.34
- MAM00307r + 2 proton + dioxygen → water + MAM02364r
→ Unbalanced · EC 1.13.11.34
- MAM01058c + water + NADP(3-) ⇌ proton + leukotriene A4 + NADPH(4-) + dioxygen
⇌ Balanced · EC 1.13.11.31, 1.13.11.34
- proton + leukotriene A4 + NADPH(4-) + dioxygen → MAM01058n + water + NADP(3-)
→ Balanced · EC 1.13.11.31, 1.13.11.34
- (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + dioxygen → MAM01041c
→ Balanced · EC 1.13.11.34
- MAM00373c + dioxygen → MAM01038c + water
→ Balanced · EC 1.13.11.34
- (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + dioxygen → MAM01041n
→ Balanced · EC 1.13.11.34
- MAM00373n + dioxygen → MAM01038n + water
→ Balanced · EC 1.13.11.34
- MAM00373r + dioxygen → MAM01038r + water
→ Balanced · EC 1.13.11.34
- MAM00373x + dioxygen → MAM01038x + water
→ Balanced · EC 1.13.11.34
- (18R)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + dioxygen → MAM01056c + water
→ Balanced · EC 1.13.11.34
- MAM00374n + dioxygen → MAM00098n + water
→ Balanced · EC 1.13.11.34
- 2 5(S)-HETE + dioxygen → 2 MAM01050n
→ Balanced · EC 1.13.11.34
- (18R)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + dioxygen → MAM01056n + water
→ Balanced · EC 1.13.11.34
- 2 MAM00307n + dioxygen → 2 MAM02364n
→ Balanced · EC 1.13.11.34
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + dioxygen → (12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate
→ Balanced
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + dioxygen → (5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate
→ Balanced
- (5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate → leukotriene A4 + water
→ Balanced
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + dioxygen → leukotriene A4 + water
→ Balanced
- (5Z,8Z,11Z,14Z)-eicosatetraenoate + dioxygen → (8S)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate
→ Balanced
- (5S)-hydroperoxy-(18S)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate → (5S,6S)-epoxy-(18S)-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate + water
→ Balanced
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid + dioxygen → (14S)-hydroperoxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate
→ Balanced
- (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + dioxygen → (5S)-hydroperoxy-(15S)-hydroxy-(6E,8Z,11Z,13E)-eicosatetraenoate
→ Balanced
- CHEBI:90825 + dioxygen → CHEBI:90826
→ Balanced
- (18S)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + dioxygen → (5S)-hydroperoxy-(18S)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate
→ Balanced
- (5S)-hydroperoxy-(18R)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate → (5S,6S)-epoxy-(18R)-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate + water
→ Balanced
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid + dioxygen → (17S)-hydroperoxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate
→ Balanced
- CHEBI:90826 → CHEBI:133812 + water
→ Balanced
- (18R)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + dioxygen → (5S)-hydroperoxy-(18R)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate
→ Balanced
- (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + dioxygen → (5S)-hydroperoxy-(6E,8Z,11Z,14Z,17Z)-eicosapentaenoate
→ Balanced
- CHEBI:145835 + dioxygen ? CHEBI:145836
? Balanced
- (12S)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + dioxygen ? (5S)-hydroperoxy-(12S)-hydroxy-(6E,8Z,10E,14Z)-eicosatetraenoate
? Balanced
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid + dioxygen → (7S)-hydroperoxy-(4Z,8E,10Z,13Z,16Z,19Z)-docosahexaenoate
→ Balanced
- (5S)-hydroperoxy-(6E,8Z,11Z,14Z,17Z)-eicosapentaenoate → leukotriene A5 + water
→ Balanced