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Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
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Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

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Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Reactions

ACSL3

166 reactions

Inferred

Reference data, not a finding. Evidence key

tetradecanoate + ATP(4-) + coenzyme A(4-) → tetradecanoyl-CoA + AMP + diphosphate(3-)
→ Balanced
dodecanoate + ATP(4-) + coenzyme A(4-) → dodecanoyl-CoA + AMP + diphosphate(3-)
→ Balanced
(9Z)-hexadecenoate + ATP(4-) + coenzyme A(4-) → (9Z)-hexadecenoyl-CoA + AMP + diphosphate(3-)
→ Balanced
(9Z,12Z)-octadecadienoate + ATP(4-) + coenzyme A(4-) → (9Z,12Z)-octadecadienoyl-CoA + AMP + diphosphate(3-)
→ Balanced
(E)-hexadec-2-enoate + ATP(4-) + coenzyme A(4-) → (2E)-hexadecenoyl-CoA + AMP + diphosphate(3-)
→ Balanced
a fatty acid + ATP(4-) + coenzyme A(4-) → a fatty acyl-CoA + AMP + diphosphate(3-)
→ Balance undeterminable
all-cis-docosa-4,7,10,13,16,19-hexaenoic acid + ATP(4-) + coenzyme A(4-) → (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + AMP + diphosphate(3-)
→ Balanced
(9Z,12Z,15Z)-octadecatrienoate + ATP(4-) + coenzyme A(4-) → (9Z,12Z,15Z)-octadecatrienoyl-CoA + AMP + diphosphate(3-)
→ Balanced
eicosanoate + ATP(4-) + coenzyme A(4-) → eicosanoyl-CoA + AMP + diphosphate(3-)
→ Balanced
a medium-chain fatty acid + ATP(4-) + coenzyme A(4-) → a medium-chain fatty acyl-CoA + AMP + diphosphate(3-)
→ Balance undeterminable
11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + ATP(4-) + coenzyme A(4-) → 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoyl-CoA + AMP + diphosphate(3-)
→ Balanced
14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoate + ATP(4-) + coenzyme A(4-) → 14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoyl-CoA + AMP + diphosphate(3-)
→ Balanced
5-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + ATP(4-) + coenzyme A(4-) → 5-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoyl-CoA + AMP + diphosphate(3-)
→ Balanced
12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + ATP(4-) + coenzyme A(4-) → 12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-CoA + AMP + diphosphate(3-)
→ Balanced
15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + ATP(4-) + coenzyme A(4-) → 15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-CoA + AMP + diphosphate(3-)
→ Balanced
(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + ATP(4-) + coenzyme A(4-) → (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + AMP + diphosphate(3-)
→ Balanced

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