N(1),N(5),N(10)-tris[(E)-p-coumaroyl]spermidine + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = N(1),N(5),N(10)-tris[(E)-caffeoyl]spermidine + 3 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 3 H(+) — reaction