(1R,4R,5S)-acoradiene + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = 2,6,9-trimethyl-13-oxatetracyclo[6.3.1.1(6,9).0(1,5)]tridecane carbocation + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + H(+) — reaction