Proteins/UNIPROT:O15014

ZNF609

ProteinUNIPROT:O15014

Transcription factor, which activates RAG1, and possibly RAG2, transcription. Through the regulation of RAG1/2 expression, may regulate thymocyte maturation. Along with NIPBL and the multiprotein complex Integrator, promotes cortical neuron migration during brain development by regulating the transcription of crucial genes in this process. Preferentially binds promoters containing paused RNA polymerase II. Up-regulates the expression of SEMA3A, NRP1, PLXND1 and GABBR2 genes, among others..

[Isoform 2]: Involved in the regulation of myoblast proliferation during myogenesis..

Function from UniProtKB (O15014), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

8 statements

8 statements · 2 reference databases · Subject: ZNF609 · Sources: gene ontology, Hetionet

Order

ADAMTS7 covaries with ZNF609ProteinHetionet hetionet:covaries:11173-23060Inferred only
FBN3 covaries with ZNF609ProteinHetionet hetionet:covaries:23060-84467Inferred only
ATXN1 interacts with ZNF609ProteinHetionet hetionet:interacts:23060-6310Inferred only
UBC interacts with ZNF609ProteinHetionet hetionet:interacts:23060-7316Inferred only
ZNF609 regulates positive regulation of neuron migrationBiological processgene ontology O15014|GO:2001224Inferred only
ZNF609 regulates positive regulation of transcription by RNA polymerase IIBiological processgene ontology O15014|GO:0045944Inferred only
ZNF609 regulates regulation of myoblast proliferationBiological processgene ontology O15014|GO:2000291Inferred only
ZNF609 regulates regulation of transcription by RNA polymerase IIBiological processgene ontology O15014|GO:0006357Inferred only

Other names

2 names

Resolves to: ZNF609

Also called: KIAA0295Zinc finger protein 609

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