Proteins/UNIPROT:Q96JP5

ZFP91

ProteinUNIPROT:Q96JP5

DNA-binding transcription factor. Also acts as an atypical E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked ubiquitination of MAP3K14/NIK, leading to stabilize and activate MAP3K14/NIK. It thereby acts as an activator of the non-canonical NF-kappa-B2/NFKB2 pathway. May also play an important role in cell proliferation and/or anti-apoptosis..

Function from UniProtKB (Q96JP5), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

7 statements

7 statements · 2 reference databases · Subject: ZFP91 · Sources: gene ontology, Hetionet

Order

ZNF662 covaries with ZFP91ProteinHetionet hetionet:covaries:389114-80829Inferred only
FOS interacts with ZFP91ProteinHetionet hetionet:interacts:2353-80829Inferred only
MAP3K14 interacts with ZFP91ProteinHetionet hetionet:interacts:80829-9020Inferred only
SUMO2 interacts with ZFP91ProteinHetionet hetionet:interacts:6613-80829Inferred only
UBC interacts with ZFP91ProteinHetionet hetionet:interacts:7316-80829Inferred only
ZFP91 regulates positive regulation of transcription by RNA polymerase IIBiological processgene ontology Q96JP5|GO:0045944Inferred only
ZFP91 regulates regulation of transcription by RNA polymerase IIBiological processgene ontology Q96JP5|GO:0006357Inferred only

Other names

5 names

Resolves to: ZFP91

Also called: RING-type E3 ubiquitin transferase ZFP91Zfp-91Zinc finger protein 757Zinc finger protein 91 homologZNF757

← Every protein Find it in the graph →