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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:Q9H0M4

ZCWPW1

Protein·UNIPROT:Q9H0M4

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Dual histone methylation reader specific for PRDM9-catalyzed histone marks (H3K4me3 and H3K36me3). Facilitates the repair of PRDM9-induced meiotic double-strand breaks (DSBs) (By similarity). Essential for male fertility and spermatogenesis (By similarity). Required for meiosis prophase I progression in male but not in female germ cells (By similarity)..

Function from UniProtKB (Q9H0M4), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

3 statements

3 statements · 2 reference databases · Subject: ZCWPW1 · Sources: gene ontology, Hetionet

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EGR1 interacts with ZCWPW1ProteinHetionet hetionet:interacts:1958-55063Inferred only
ZCWPW1 regulates positive regulation of DNA recombinationBiological processgene ontology Q9H0M4|GO:0045911Inferred only
ZCWPW1 regulates positive regulation of double-strand break repairBiological processgene ontology Q9H0M4|GO:2000781Inferred only

Other names

1 name

Resolves to: ZCWPW1

Also called: Zinc finger CW-type PWWP domain protein 1

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