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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:Q6UW78

UQCC3

Protein·UNIPROT:Q6UW78

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Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex), mediating cytochrome b recruitment and probably stabilization within the complex. Thereby, plays an important role in ATP production by mitochondria. Cardiolipin-binding protein, it may also control the cardiolipin composition of mitochondria membranes and their morphology..

Function from UniProtKB (Q6UW78), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

2 rows

mitochondrial complex III deficiency has a germline basis in UQCC3DiseaseGenCC HGNC:34399|MONDO:0015448Inferred only
mitochondrial complex III deficiency nuclear type 9 has a germline basis in UQCC3DiseaseGenCC HGNC:34399|MONDO:0014496Inferred only

Statements

5 statements

5 statements · 2 reference databases · Subject: UQCC3 · Sources: Hetionet, Reactome

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UBC interacts with UQCC3ProteinHetionet hetionet:interacts:7316-790955Inferred only
UQCC3 participates in Aerobic respiration and respiratory electron transportPathwayReactome R-HSA-1428517Inferred only
UQCC3 participates in Complex III assemblyPathwayReactome R-HSA-9865881Inferred only
UQCC3 participates in MetabolismPathwayReactome R-HSA-1430728Inferred only
UQCC3 participates in Respiratory electron transportPathwayReactome R-HSA-611105Inferred only

Other names

3 names

Resolves to: UQCC3

Also called: Assembly factor CBP4 homologC11orf83Ubiquinol-cytochrome-c reductase complex assembly factor 3

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