TTC4

Co-chaperone that recruits molecular chaperones Hsp90 (HSC82 and HSP82) and Hsp70 (SSA1) to nascent polypeptides, facilitating their proper folding into functional proteins. Client proteins include eukaryotic elongation factor eEF2, a key player in cellular translation. Stimulates SSA1 ATPase activity, but not Hsp90 ATPase activity (By similarity). Promotes Sendai virus (SeV)-induced host cell innate immune responses..

Function from UniProtKB (O95801), read 2026-09-23. CC BY 4.0.