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Proteins/UNIPROT:Q8NG06
E3 ubiquitin ligase induced during late erythropoiesis. Directly binds and ubiquitinates the intermediate chain of the microtubule motor dynein (DYNC1LI1/DYNC1LI2), stimulating the degradation of the dynein holoprotein complex. May participate in the erythroblast enucleation process through regulation of nuclear polarization..
Function from UniProtKB (Q8NG06), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
7 statements
7 statements · 2 reference databases · Subject: TRIM58 · Sources: gene ontology, Hetionet
4 names
Resolves to: TRIM58