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Proteins/UNIPROT:P02585

TNNC2

Protein·UNIPROT:P02585

Open in the graph

Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments..

Function from UniProtKB (P02585), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

1 row

congenital myopathy 15 has a germline basis in TNNC2DiseaseGenCC HGNC:11944|MONDO:0859335Inferred only

Statements

6 statements

6 statements · 4 reference databases · Subject: TNNC2 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

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TNNC2 interacts with TNNI2ProteinHetionet hetionet:interacts:7125-7136Inferred only
TNNC2 participates in Caffeine in myocytesPathwayWikiPathways WP5603Inferred only
TNNC2 participates in Muscle contractionPathwayReactome R-HSA-397014Inferred only
TNNC2 participates in Striated Muscle ContractionPathwayReactome R-HSA-390522Inferred only
TNNC2 participates in Striated muscle contraction pathwayPathwayWikiPathways WP383Inferred only
TNNC2 regulates regulation of muscle contractionBiological processgene ontology P02585|GO:0006937Inferred only

Other names

1 name

Resolves to: TNNC2

Also called: Troponin C, skeletal muscle

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