Proteins/UNIPROT:Q5SNT2

TMEM201

ProteinUNIPROT:Q5SNT2

Critical regulator of angiogenesis and endothelial cell (EC) migration. Promotes the migration of endothelial cells, which is essential for angiogenesis. Interacts with the linker of nucleoskeleton and cytoskeleton (LINC) complex, which plays a vital role in connecting the cell's cytoskeleton to the nuclear envelope. This interaction is essential for maintaining cellular structure and facilitating the movement of endothelial cells, which is critical for proper vascular development. Involved in nuclear movement during fibroblast polarization and migration (By similarity). Overexpression can recruit Ran GTPase to the nuclear periphery..

[Isoform 2]: May define a distinct membrane domain in the vicinity of the mitotic spindle. Involved in the organization of the nuclear envelope implicating EMD, SUN1 and A-type lamina..

Function from UniProtKB (Q5SNT2), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

6 statements

6 statements · 2 reference databases · Subject: TMEM201 · Sources: gene ontology, Hetionet

Order

TMEM201 covaries with CSPG5ProteinHetionet hetionet:covaries:10675-199953Inferred only
TMEM201 covaries with F2RL3ProteinHetionet hetionet:covaries:199953-9002Inferred only
TMEM201 covaries with FLYWCH2ProteinHetionet hetionet:covaries:114984-199953Inferred only
TMEM201 covaries with OR9G9ProteinHetionet hetionet:covaries:199953-504191Inferred only
UBC interacts with TMEM201ProteinHetionet hetionet:interacts:199953-7316Inferred only
TMEM201 regulates positive regulation of endothelial cell migrationBiological processgene ontology Q5SNT2|GO:0010595Inferred only

Other names

4 names

Resolves to: TMEM201

Also called: NET5SAMP1Spindle-associated membrane protein 1Transmembrane protein 201

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