Proteins/UNIPROT:A0AVI4

TMEM129

ProteinUNIPROT:A0AVI4

E3 ubiquitin-protein ligase involved in ER-associated protein degradation, preferentially associates with the E2 enzyme UBE2J2. Exploited by viral US11 proteins to mediate HLA class I proteins degradation..

Function from UniProtKB (A0AVI4), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

7 statements

7 statements · 3 reference databases · Subject: TMEM129 · Sources: Hetionet, Reactome, WikiPathways

Order

FAM20C covaries with TMEM129ProteinHetionet hetionet:covaries:56975-92305Inferred only
UBC interacts with TMEM129ProteinHetionet hetionet:interacts:7316-92305Inferred only
TMEM129 participates in 4p16 3 copy number variationPathwayWikiPathways WP5365Inferred only
TMEM129 participates in E3 ubiquitin ligases ubiquitinate target proteinsPathwayReactome R-HSA-8866654Inferred only
TMEM129 participates in Metabolism of proteinsPathwayReactome R-HSA-392499Inferred only
TMEM129 participates in Post-translational protein modificationPathwayReactome R-HSA-597592Inferred only
TMEM129 participates in Protein ubiquitinationPathwayReactome R-HSA-8852135Inferred only

Other names

1 name

Resolves to: TMEM129

Also called: RING-type E3 ubiquitin transferase TM129

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