Proteins/UNIPROT:Q9NPL8

TIMMDC1

ProteinUNIPROT:Q9NPL8

Chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Participates in constructing the membrane arm of complex I..

Function from UniProtKB (Q9NPL8), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

3 rows

mitochondrial complex I deficiency has a germline basis in TIMMDC1DiseaseGenCC HGNC:1321|MONDO:0100133Inferred only
mitochondrial complex I deficiency, nuclear type 31 has a germline basis in TIMMDC1DiseaseGenCC HGNC:1321|MONDO:0032634Inferred only
mitochondrial disease has a germline basis in TIMMDC1DiseaseGenCC HGNC:1321|MONDO:0044970Inferred only

Statements

10 statements

10 statements · 3 reference databases · Subject: TIMMDC1 · Sources: Hetionet, Reactome, WikiPathways

Order

TIMMDC1 covaries with NKX2-8ProteinHetionet hetionet:covaries:26257-51300Inferred only
APP interacts with TIMMDC1ProteinHetionet hetionet:interacts:351-51300Inferred only
HGS interacts with TIMMDC1ProteinHetionet hetionet:interacts:51300-9146Inferred only
UBC interacts with TIMMDC1ProteinHetionet hetionet:interacts:51300-7316Inferred only
TIMMDC1 participates in Aerobic respiration and respiratory electron transportPathwayReactome R-HSA-1428517Inferred only
TIMMDC1 participates in Complex I biogenesisPathwayReactome R-HSA-6799198Inferred only
TIMMDC1 participates in Disorders of mitochondrial homeostatis dynamics protein import and quality controlPathwayWikiPathways WP5504Inferred only
TIMMDC1 participates in MetabolismPathwayReactome R-HSA-1430728Inferred only
TIMMDC1 participates in Mitochondrial complex I assembly model OXPHOS systemPathwayWikiPathways WP4324Inferred only
TIMMDC1 participates in Respiratory electron transportPathwayReactome R-HSA-611105Inferred only

Other names

5 names

Resolves to: TIMMDC1

Also called: C3orf1M5-14Protein M5-14TIMM domain containing protein 1Translocase of inner mitochondrial membrane domain-containing protein 1

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