Proteins/UNIPROT:Q9BVV7

TIMM21

ProteinUNIPROT:Q9BVV7

Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex. Probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes..

Function from UniProtKB (Q9BVV7), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

11 statements

11 statements · 2 reference databases · Subject: TIMM21 · Sources: Hetionet, Reactome

Order

TIMM21 covaries with FAM186BProteinHetionet hetionet:covaries:29090-84070Inferred only
TIMM21 covaries with FASTKD3ProteinHetionet hetionet:covaries:29090-79072Inferred only
TIMM21 covaries with GTF3C6ProteinHetionet hetionet:covaries:112495-29090Inferred only
TIMM21 covaries with NUBP2ProteinHetionet hetionet:covaries:10101-29090Inferred only
UBC interacts with TIMM21ProteinHetionet hetionet:interacts:29090-7316Inferred only
TIMM21 participates in Aerobic respiration and respiratory electron transportPathwayReactome R-HSA-1428517Inferred only
TIMM21 participates in Complex IV assemblyPathwayReactome R-HSA-9864848Inferred only
TIMM21 participates in MetabolismPathwayReactome R-HSA-1430728Inferred only
TIMM21 participates in Mitochondrial protein importPathwayReactome R-HSA-1268020Inferred only
TIMM21 participates in Protein localizationPathwayReactome R-HSA-9609507Inferred only
TIMM21 participates in Respiratory electron transportPathwayReactome R-HSA-611105Inferred only

Other names

4 names

Resolves to: TIMM21

Also called: C18orf55Mitochondrial import inner membrane translocase subunit Tim21TIM21TIM21-like protein, mitochondrial

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