Proteins/UNIPROT:Q86YJ6

THNSL2

ProteinUNIPROT:Q86YJ6

[Isoform 1]: Acts as a catabolic phospho-lyase on both gamma- and beta-phosphorylated substrates. Degrades O-phospho-threonine (PThr) to alpha-ketobutyrate, ammonia and phosphate (By similarity)..

[Isoform SOFAT]: Potent inducer of osteoblastic production of IL6. May act to exacerbate inflammation and/or bone turnover under inflammatory conditions..

Function from UniProtKB (Q86YJ6), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

4 statements

4 statements · 2 reference databases · Subject: THNSL2 · Sources: Hetionet, UniProt

Order

THNSL2 covaries with CSPG5ProteinHetionet hetionet:covaries:10675-55258Inferred only
ARPC3 interacts with THNSL2ProteinHetionet hetionet:interacts:10094-55258Inferred only
ZBTB16 interacts with THNSL2ProteinHetionet hetionet:interacts:55258-7704Inferred only
THNSL2 requires the cofactor pyridoxal 5'-phosphateCompoundUniProt Q86YJ6Inferred only

Other names

3 names

Resolves to: THNSL2

Also called: Secreted osteoclastogenic factor of activated T-cellsSOFATTSH2

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