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A reference for what the literature reports. Not medical advice.

Proteins/UNIPROT:Q5TEJ8

THEMIS2

Protein·UNIPROT:Q5TEJ8

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May constitute a control point in macrophage inflammatory response, promoting LPS-induced TLR4-mediated TNF production. Determines the threshold for activation of B cells by low-affinity and low-avidity ligands via PLCG2 activation and its downstream pathways (By similarity)..

Function from UniProtKB (Q5TEJ8), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

2 statements

2 statements · 2 reference databases · Subject: THEMIS2 · Sources: gene ontology, Hetionet

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IL17REL covaries with THEMIS2ProteinHetionet hetionet:covaries:400935-9473Inferred only
THEMIS2 regulates regulation of B cell activationBiological processgene ontology Q5TEJ8|GO:0050864Inferred only

Other names

6 names

Resolves to: THEMIS2

Also called: C1orf38ICB-1ICB1Induced by contact to basement membrane 1 proteinProtein ICB-1Thymocyte-expressed molecule involved in selection protein 2

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