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Proteins/UNIPROT:P59533

TAS2R38

Protein·UNIPROT:P59533

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Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity)..

Function from UniProtKB (P59533), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

11 statements

11 statements · 3 reference databases · Subject: TAS2R38 · Sources: Hetionet, Reactome, WikiPathways

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TAS2R38 covaries with PER2ProteinHetionet hetionet:covaries:5726-8864Inferred only
TAS2R38 participates in Class C/3 (Metabotropic glutamate/pheromone receptors)PathwayReactome R-HSA-420499Inferred only
TAS2R38 participates in G alpha (i) signalling eventsPathwayReactome R-HSA-418594Inferred only
TAS2R38 participates in GPCR downstream signallingPathwayReactome R-HSA-388396Inferred only
TAS2R38 participates in GPCR ligand bindingPathwayReactome R-HSA-500792Inferred only
TAS2R38 participates in Male infertilityPathwayWikiPathways WP4673Inferred only
TAS2R38 participates in Sensory PerceptionPathwayReactome R-HSA-9709957Inferred only
TAS2R38 participates in Sensory perception of sweet, bitter, and umami (glutamate) tastePathwayReactome R-HSA-9717207Inferred only
TAS2R38 participates in Sensory perception of tastePathwayReactome R-HSA-9717189Inferred only
TAS2R38 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
TAS2R38 participates in Signaling by GPCRPathwayReactome R-HSA-372790Inferred only

Other names

5 names

Resolves to: TAS2R38

Also called: PTCPTC bitter taste receptorT2R38T2R61Taste receptor type 2 member 61

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