Proteins/UNIPROT:Q86UU9

TAC4

ProteinUNIPROT:Q86UU9

Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Endokinin-A induces thermal hyperalgesia and pain-related behavior such as scratching following intrathecal administration in rats. These effects are suppressed by treatment with endokinin-C. Endokinin-A/B reduces arterial blood pressure and increases sperm motility..

Function from UniProtKB (Q86UU9), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

10 statements

10 statements · 3 reference databases · Subject: TAC4 · Sources: gene ontology, Hetionet, WikiPathways

Order

TAC1 interacts with TAC4ProteinHetionet hetionet:interacts:255061-6863Inferred only
TACR1 interacts with TAC4ProteinHetionet hetionet:interacts:255061-6869Inferred only
TACR2 interacts with TAC4ProteinHetionet hetionet:interacts:255061-6865Inferred only
TACR3 interacts with TAC4ProteinHetionet hetionet:interacts:255061-6870Inferred only
TAC4 participates in Peptide GPCRsPathwayWikiPathways WP24Inferred only
TAC4 regulates negative regulation of sensory perception of painBiological processgene ontology Q86UU9|GO:1904057Inferred only
TAC4 regulates negative regulation of systemic arterial blood pressureBiological processgene ontology Q86UU9|GO:0003085Inferred only
TAC4 regulates positive regulation of cytosolic calcium ion concentrationBiological processgene ontology Q86UU9|GO:0007204Inferred only
TAC4 regulates positive regulation of flagellated sperm motilityBiological processgene ontology Q86UU9|GO:1902093Inferred only
TAC4 regulates regulation of sensory perception of painBiological processgene ontology Q86UU9|GO:0051930Inferred only

Other names

6 names

Resolves to: TAC4

Also called: ; Endokinin-CEKAEKA/BEKCPPT-CPreprotachykinin-C

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