Proteins/UNIPROT:Q9Y6J8

STYXL1

ProteinUNIPROT:Q9Y6J8

Catalytically inactive phosphatase. By binding to G3BP1, inhibits the formation of G3BP1-induced stress granules. Does not act by protecting the dephosphorylation of G3BP1 at 'Ser-149'. Inhibits PTPMT1 phosphatase activity. By inhibiting PTPMT1, positively regulates intrinsic apoptosis. May play a role in the formation of neurites during neuronal development..

Function from UniProtKB (Q9Y6J8), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

19 statements

19 statements · 3 reference databases · Subject: STYXL1 · Sources: gene ontology, Hetionet, WikiPathways

Order

STYXL1 covaries with APOBRProteinHetionet hetionet:covaries:51657-55911Inferred only
TGFBR1 interacts with STYXL1ProteinHetionet hetionet:interacts:51657-7046Inferred only
UBC interacts with STYXL1ProteinHetionet hetionet:interacts:51657-7316Inferred only
STYXL1 participates in 7q11 23 distal copy number variationPathwayWikiPathways WP5401Inferred only
STYXL1 regulates negative regulation of stress granule assemblyBiological processgene ontology Q9Y6J8|GO:0062030Inferred only
STYXL1 regulates positive regulation of intrinsic apoptotic signaling pathwayBiological processgene ontology Q9Y6J8|GO:2001244Inferred only
STYXL1 regulates positive regulation of neuron projection developmentBiological processgene ontology Q9Y6J8|GO:0010976Inferred only
STYXL1 regulates regulation of intrinsic apoptotic signaling pathwayBiological processgene ontology Q9Y6J8|GO:2001242Inferred only
APC increases the expression of STYXL1ProteinHetionet hetionet:regulates:324-51657Inferred only
CDK4 increases the expression of STYXL1ProteinHetionet hetionet:regulates:1019-51657Inferred only
DDX49 increases the expression of STYXL1ProteinHetionet hetionet:regulates:54555-51657Inferred only
FABP4 decreases the expression of STYXL1ProteinHetionet hetionet:regulates:2167-51657Inferred only

Show the remaining 7

GCAT increases the expression of STYXL1ProteinHetionet hetionet:regulates:23464-51657Inferred only
MYB decreases the expression of STYXL1ProteinHetionet hetionet:regulates:4602-51657Inferred only
PCK1 decreases the expression of STYXL1ProteinHetionet hetionet:regulates:5105-51657Inferred only
RAB21 decreases the expression of STYXL1ProteinHetionet hetionet:regulates:23011-51657Inferred only
RFC2 decreases the expression of STYXL1ProteinHetionet hetionet:regulates:5982-51657Inferred only
SPDEF decreases the expression of STYXL1ProteinHetionet hetionet:regulates:25803-51657Inferred only
TMED10 increases the expression of STYXL1ProteinHetionet hetionet:regulates:10972-51657Inferred only

Other names

6 names

Resolves to: STYXL1

Also called: Dual specificity phosphatase inhibitor MK-STYXDual specificity protein phosphatase 24DUSP24Inactive dual specificity protein phosphatase MK-STYXMap kinase phosphatase-like protein MK-STYXMKSTYX

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