Proteins/UNIPROT:Q9ULZ2

STAP1

ProteinUNIPROT:Q9ULZ2

In BCR signaling, appears to function as a docking protein acting downstream of TEC and participates in a positive feedback loop by increasing the activity of TEC..

Function from UniProtKB (Q9ULZ2), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

17 statements

17 statements · 2 reference databases · Subject: STAP1 · Sources: gene ontology, Hetionet

Order

DDIT4L covaries with STAP1ProteinHetionet hetionet:covaries:115265-26228Inferred only
STAP1 covaries with FAM171A2ProteinHetionet hetionet:covaries:26228-284069Inferred only
STAP1 covaries with KANSL1LProteinHetionet hetionet:covaries:151050-26228Inferred only
STAP1 covaries with NIF3L1ProteinHetionet hetionet:covaries:26228-60491Inferred only
KIT interacts with STAP1ProteinHetionet hetionet:interacts:26228-3815Inferred only
PTK2B interacts with STAP1ProteinHetionet hetionet:interacts:2185-26228Inferred only
STAP1 interacts with SH3KBP1ProteinHetionet hetionet:interacts:26228-30011Inferred only
TEC interacts with STAP1ProteinHetionet hetionet:interacts:26228-7006Inferred only
STAP1 regulates negative regulation of macrophage chemotaxisBiological processgene ontology Q9ULZ2|GO:0010760Inferred only
STAP1 regulates negative regulation of macrophage colony-stimulating factor signaling pathwayBiological processgene ontology Q9ULZ2|GO:1902227Inferred only
STAP1 regulates negative regulation of microglial cell migrationBiological processgene ontology Q9ULZ2|GO:1904140Inferred only
STAP1 regulates negative regulation of ruffle assemblyBiological processgene ontology Q9ULZ2|GO:1900028Inferred only

Show the remaining 5

STAP1 regulates positive regulation of B cell receptor signaling pathwayBiological processgene ontology Q9ULZ2|GO:0050861Inferred only
STAP1 regulates positive regulation of gene expressionBiological processgene ontology Q9ULZ2|GO:0010628Inferred only
STAP1 regulates positive regulation of microglial cell activationBiological processgene ontology Q9ULZ2|GO:1903980Inferred only
STAP1 regulates positive regulation of microglial cell mediated cytotoxicityBiological processgene ontology Q9ULZ2|GO:1904151Inferred only
STAP1 regulates positive regulation of phagocytosis, engulfmentBiological processgene ontology Q9ULZ2|GO:0060100Inferred only

Other names

5 names

Resolves to: STAP1

Also called: BCR downstream-signaling protein 1BRDG1Docking protein BRDG1STAP-1Stem cell adaptor protein 1

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