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Proteins/UNIPROT:Q6UWN8

SPINK6

Protein·UNIPROT:Q6UWN8

Open in the graph

Serine protease inhibitor selective for kallikreins. Efficiently inhibits KLK4, KLK5, KLK6, KLK7, KLK12, KLK13 and KLK14. Doesn't inhibit KLK8..

Function from UniProtKB (Q6UWN8), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

6 statements

6 statements · 4 reference databases · Subject: SPINK6 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

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APP interacts with SPINK6ProteinHetionet hetionet:interacts:351-404203Inferred only
SPINK6 participates in Developmental BiologyPathwayReactome R-HSA-1266738Inferred only
SPINK6 participates in Formation of the cornified envelopePathwayReactome R-HSA-6809371Inferred only
SPINK6 participates in Hair follicle development cytodifferentiation stage 3 of 3PathwayWikiPathways WP2840Inferred only
SPINK6 participates in KeratinizationPathwayReactome R-HSA-6805567Inferred only
SPINK6 regulates negative regulation of proteolysisBiological processgene ontology Q6UWN8|GO:0045861Inferred only

Other names

2 names

Resolves to: SPINK6

Also called: Kallikrein inhibitorSerine protease inhibitor Kazal-type 6

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