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Proteins/UNIPROT:Q86XE0
Involved in endosomal trafficking of cargo proteins, including transferrin-bound transferrin receptor (TFRC), cation-independent mannose-6-phosphate receptor (IGF2R) and epidermal growth factor receptor (EGFR). Functions redundantly with other BAR domain-containing sorting nexins in endosome to trans-Golgi network transport of IGF2R. Regulates in coordination with SNX5 sorting and trafficking of EGF-activated EGFR to multivesicular bodies for lysosomal degradation. Plays an essential role in neurite outgrowth, controlling basigin/EMMPRIN (BSG) trafficking to the cell surface (By similarity)..
Function from UniProtKB (Q86XE0), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
4 statements
4 statements · 2 reference databases · Subject: SNX32 · Sources: gene ontology, Hetionet
3 names
Resolves to: SNX32