Proteins/UNIPROT:Q4G0N8

SLC9C1

ProteinUNIPROT:Q4G0N8

Sperm-specific solute carrier involved in intracellular pH regulation of spermatozoa. Required for sperm motility and fertility. Involved in sperm cell hyperactivation, a step needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for the expression and bicarbonate regulation of the soluble adenylyl cyclase (ADCY10)..

Function from UniProtKB (Q4G0N8), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

5 statements

5 statements · 3 reference databases · Subject: SLC9C1 · Sources: gene ontology, Hetionet, Reactome

Order

SLC9C1 covaries with SLC9C2ProteinHetionet hetionet:covaries:284525-285335Inferred only
SLC9C1 participates in Ion channel transportPathwayReactome R-HSA-983712Inferred only
SLC9C1 participates in Stimuli-sensing channelsPathwayReactome R-HSA-2672351Inferred only
SLC9C1 participates in Transport of small moleculesPathwayReactome R-HSA-382551Inferred only
SLC9C1 regulates regulation of intracellular pHBiological processgene ontology Q4G0N8|GO:0051453Inferred only

Other names

7 names

Resolves to: SLC9C1

Also called: Na(+)/H(+) exchanger 10NHE-10SLC9A10sNHESodium/hydrogen exchanger 10Solute carrier family 9 member 10Sperm-specific Na(+)/H(+) exchanger

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