Proteins/UNIPROT:Q9H6Q3

SLA2

ProteinUNIPROT:Q9H6Q3

Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins..

Function from UniProtKB (Q9H6Q3), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

14 statements

14 statements · 3 reference databases · Subject: SLA2 · Sources: gene ontology, Hetionet, Reactome

Order

CBL interacts with SLA2ProteinHetionet hetionet:interacts:84174-867Inferred only
ERBB2 interacts with SLA2ProteinHetionet hetionet:interacts:2064-84174Inferred only
LAMC2 interacts with SLA2ProteinHetionet hetionet:interacts:3918-84174Inferred only
SMURF2 interacts with SLA2ProteinHetionet hetionet:interacts:64750-84174Inferred only
UBC interacts with SLA2ProteinHetionet hetionet:interacts:7316-84174Inferred only
ZAP70 interacts with SLA2ProteinHetionet hetionet:interacts:7535-84174Inferred only
SLA2 participates in Cytokine Signaling in Immune systemPathwayReactome R-HSA-1280215Inferred only
SLA2 participates in FLT3 SignalingPathwayReactome R-HSA-9607240Inferred only
SLA2 participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
SLA2 participates in Negative regulation of FLT3PathwayReactome R-HSA-9706369Inferred only
SLA2 regulates negative regulation of calcium-mediated signalingBiological processgene ontology Q9H6Q3|GO:0050849Inferred only
SLA2 regulates negative regulation of T cell receptor signaling pathwayBiological processgene ontology Q9H6Q3|GO:0050860Inferred only

Show the remaining 2

SLA2 regulates negative regulation of transcription by RNA polymerase IIBiological processgene ontology Q9H6Q3|GO:0000122Inferred only
SLA2 regulates regulation of immune responseBiological processgene ontology Q9H6Q3|GO:0050776Inferred only

Other names

6 names

Resolves to: SLA2

Also called: C20orf156MARSModulator of antigen receptor signalingSLAP-2SLAP2Src-like adapter protein 2

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