Proteins/UNIPROT:Q9BQI5

SGIP1

ProteinUNIPROT:Q9BQI5

May function in clathrin-mediated endocytosis. Has both a membrane binding/tubulating activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a preference for membranes enriched in phosphatidylserine and phosphoinositides and is required for the endocytosis of the transferrin receptor. May also bind tubulin. May play a role in the regulation of energy homeostasis..

Function from UniProtKB (Q9BQI5), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

8 statements

8 statements · 3 reference databases · Subject: SGIP1 · Sources: gene ontology, Hetionet, Reactome

Order

AMPH interacts with SGIP1ProteinHetionet hetionet:interacts:273-84251Inferred only
PHB1 interacts with SGIP1ProteinHetionet hetionet:interacts:5245-84251Inferred only
SGIP1 participates in Cargo recognition for clathrin-mediated endocytosisPathwayReactome R-HSA-8856825Inferred only
SGIP1 participates in Clathrin-mediated endocytosisPathwayReactome R-HSA-8856828Inferred only
SGIP1 participates in Membrane TraffickingPathwayReactome R-HSA-199991Inferred only
SGIP1 participates in Vesicle-mediated transportPathwayReactome R-HSA-5653656Inferred only
SGIP1 regulates positive regulation of feeding behaviorBiological processgene ontology Q9BQI5|GO:2000253Inferred only
SGIP1 regulates positive regulation of receptor-mediated endocytosisBiological processgene ontology Q9BQI5|GO:0048260Inferred only

Other names

2 names

Resolves to: SGIP1

Also called: Endophilin-3-interacting proteinSH3-containing GRB2-like protein 3-interacting protein 1

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