Proteins/UNIPROT:Q96JE7

SEC16B

ProteinUNIPROT:Q96JE7

Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. Involved in peroxisome biogenesis. Regulates the transport of peroxisomal biogenesis factors PEX3 and PEX16 from the ER to peroxisomes..

Function from UniProtKB (Q96JE7), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

1 row

autosomal dominant polycystic liver disease has a germline basis in SEC16BDiseaseGenCC HGNC:30301|MONDO:0000447Inferred only

Statements

15 statements

15 statements · 4 reference databases · Subject: SEC16B · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

ADGRE1 covaries with SEC16BProteinHetionet hetionet:covaries:2015-89866Inferred only
CCR6 covaries with SEC16BProteinHetionet hetionet:covaries:1235-89866Inferred only
PKD1L3 covaries with SEC16BProteinHetionet hetionet:covaries:342372-89866Inferred only
TBC1D2B covaries with SEC16BProteinHetionet hetionet:covaries:23102-89866Inferred only
SEC13 interacts with SEC16BProteinHetionet hetionet:interacts:6396-89866Inferred only
SEC16B participates in Asparagine N-linked glycosylationPathwayReactome R-HSA-446203Inferred only
SEC16B participates in COPII-mediated vesicle transportPathwayReactome R-HSA-204005Inferred only
SEC16B participates in ER to Golgi Anterograde TransportPathwayReactome R-HSA-199977Inferred only
SEC16B participates in Membrane TraffickingPathwayReactome R-HSA-199991Inferred only
SEC16B participates in Metabolism of proteinsPathwayReactome R-HSA-392499Inferred only
SEC16B participates in Post-translational protein modificationPathwayReactome R-HSA-597592Inferred only
SEC16B participates in Regucalcin in proximal tubule epithelial kidney cellsPathwayWikiPathways WP4838Inferred only

Show the remaining 3

SEC16B participates in Transport to the Golgi and subsequent modificationPathwayReactome R-HSA-948021Inferred only
SEC16B participates in Vesicle-mediated transportPathwayReactome R-HSA-5653656Inferred only
SEC16B regulates positive regulation of gene expressionBiological processgene ontology Q96JE7|GO:0010628Inferred only

Other names

8 names

Resolves to: SEC16B

Also called: KIAA1928Leucine zipper transcription regulator 2LZTR2Regucalcin gene promoter region-related protein p117RGPRRGPR-p117SEC16 homolog BSEC16S

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