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Proteins/UNIPROT:Q9NSC2

SALL1

Protein·UNIPROT:Q9NSC2

Open in the graph

Transcriptional repressor involved in organogenesis. Plays an essential role in ureteric bud invasion during kidney development..

Function from UniProtKB (Q9NSC2), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

2 rows

Townes-Brocks syndrome has a germline basis in SALL1DiseaseGenCC HGNC:10524|MONDO:0007142Inferred only
Townes-Brocks syndrome 1 has a germline basis in SALL1DiseaseGenCC HGNC:10524|MONDO:0054581Inferred only

Statements

26 statements

26 statements · 4 reference databases · Subject: SALL1 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

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SALL1 covaries with PGBD2ProteinHetionet hetionet:covaries:267002-6299Inferred only
CTNNB1 interacts with SALL1ProteinHetionet hetionet:interacts:1499-6299Inferred only
HDAC1 interacts with SALL1ProteinHetionet hetionet:interacts:3065-6299Inferred only
HDAC2 interacts with SALL1ProteinHetionet hetionet:interacts:3066-6299Inferred only
SALL1 interacts with SUMO1ProteinHetionet hetionet:interacts:6299-7341Inferred only
SALL1 interacts with SUMO2ProteinHetionet hetionet:interacts:6299-6613Inferred only
SALL1 interacts with TERF1ProteinHetionet hetionet:interacts:6299-7013Inferred only
SALL1 interacts with UBCProteinHetionet hetionet:interacts:6299-7316Inferred only
SALL1 interacts with UBE2IProteinHetionet hetionet:interacts:6299-7329Inferred only
SALL1 participates in Development of ureteric derived collecting systemPathwayWikiPathways WP5053Inferred only
SALL1 participates in Developmental BiologyPathwayReactome R-HSA-1266738Inferred only
SALL1 participates in Formation of the ureteric budPathwayReactome R-HSA-9830674Inferred only

Show the remaining 14

SALL1 participates in GDNF RET signaling axisPathwayWikiPathways WP4830Inferred only
SALL1 participates in Kidney developmentPathwayReactome R-HSA-9830369Inferred only
SALL1 participates in Markers of kidney cell lineagePathwayWikiPathways WP5236Inferred only
SALL1 participates in POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferationPathwayReactome R-HSA-2892247Inferred only
SALL1 participates in Transcriptional regulation of pluripotent stem cellsPathwayReactome R-HSA-452723Inferred only
SALL1 regulates negative regulation of DNA-templated transcriptionBiological processgene ontology Q9NSC2|GO:0045892Inferred only
SALL1 regulates negative regulation of transcription by RNA polymerase IIBiological processgene ontology Q9NSC2|GO:0000122Inferred only
SALL1 regulates positive regulation of DNA-templated transcriptionBiological processgene ontology Q9NSC2|GO:0045893Inferred only
SALL1 regulates positive regulation of transcription by RNA polymerase IIBiological processgene ontology Q9NSC2|GO:0045944Inferred only
SALL1 regulates positive regulation of Wnt signaling pathwayBiological processgene ontology Q9NSC2|GO:0030177Inferred only
SALL1 regulates regulation of transcription by RNA polymerase IIBiological processgene ontology Q9NSC2|GO:0006357Inferred only
DYRK3 increases the expression of SALL1ProteinHetionet hetionet:regulates:8444-6299Inferred only
GNE increases the expression of SALL1ProteinHetionet hetionet:regulates:10020-6299Inferred only
SUPV3L1 decreases the expression of SALL1ProteinHetionet hetionet:regulates:6832-6299Inferred only

Other names

8 names

Resolves to: SALL1

Also called: HSal1Sal-1SAL1Spalt-like transcription factor 1Zinc finger protein 794Zinc finger protein SALL1Zinc finger protein Spalt-1ZNF794

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