Proteins/UNIPROT:Q9H4H8

SACK1D

ProteinUNIPROT:Q9H4H8

Through the degradation of FBXW7, may act indirectly on the expression and downstream signaling of MTOR, JUN and MYC. May play also a role in cell proliferation through activation of the ERK1/ERK2 signaling cascade. May also be important for proper chromosome congression and alignment during mitosis through its interaction with KIF22..

Function from UniProtKB (Q9H4H8), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

14 statements

14 statements · 3 reference databases · Subject: SACK1D · Sources: gene ontology, Hetionet, Reactome

Order

SACK1D covaries with NADKProteinHetionet hetionet:covaries:65220-81610Inferred only
CSNK1E interacts with SACK1DProteinHetionet hetionet:interacts:1454-81610Inferred only
DYNC1I1 interacts with SACK1DProteinHetionet hetionet:interacts:1780-81610Inferred only
GADD45A interacts with SACK1DProteinHetionet hetionet:interacts:1647-81610Inferred only
GSK3B interacts with SACK1DProteinHetionet hetionet:interacts:2932-81610Inferred only
UBC interacts with SACK1DProteinHetionet hetionet:interacts:7316-81610Inferred only
UBD interacts with SACK1DProteinHetionet hetionet:interacts:10537-81610Inferred only
SACK1D participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
SACK1D participates in Signaling by EGFRPathwayReactome R-HSA-177929Inferred only
SACK1D participates in Signaling by Receptor Tyrosine KinasesPathwayReactome R-HSA-9006934Inferred only
SACK1D regulates positive regulation of cell cycle G1/S phase transitionBiological processgene ontology Q9H4H8|GO:1902808Inferred only
SACK1D regulates regulation of ERK1 and ERK2 cascadeBiological processgene ontology Q9H4H8|GO:0070372Inferred only

Show the remaining 2

SACK1D regulates regulation of protein catabolic processBiological processgene ontology Q9H4H8|GO:0042176Inferred only
SACK1D regulates regulation of TOR signalingBiological processgene ontology Q9H4H8|GO:0032006Inferred only

Other names

4 names

Resolves to: SACK1D

Also called: C20orf129FAM83DProtein FAM83DSpindle protein CHICA

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