Proteins/UNIPROT:P10155

RO60

ProteinUNIPROT:P10155

RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs. Binds to endogenous Alu retroelements which are induced by type I interferon and stimulate porinflammatory cytokine secretion. Regulates the expression of Alu retroelements as well as inflammatory genes. May play roles in cilia formation and/or maintenance (By similarity)..

Function from UniProtKB (P10155), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

7 statements

7 statements · 2 reference databases · Subject: RO60 · Sources: gene ontology, Hetionet

Order

ZNF226 covaries with RO60ProteinHetionet hetionet:covaries:6738-7769Inferred only
RO60 interacts with CUL3ProteinHetionet hetionet:interacts:6738-8452Inferred only
RO60 interacts with RAB11FIP5ProteinHetionet hetionet:interacts:26056-6738Inferred only
RO60 interacts with SSBProteinHetionet hetionet:interacts:6738-6741Inferred only
TRIM21 interacts with RO60ProteinHetionet hetionet:interacts:6737-6738Inferred only
RO60 interacts with UBCProteinHetionet hetionet:interacts:6738-7316Inferred only
RO60 regulates regulation of gene expressionBiological processgene ontology P10155|GO:0010468Inferred only

Other names

12 names

Resolves to: RO60

Also called: 60 kDa ribonucleoprotein Ro60 kDa Ro protein60 kDa SS-A/Ro ribonucleoproteinRo 60 kDa autoantigenRo60 autoantigenRoRNPSjoegren syndrome antigen A2Sjoegren syndrome type A antigenSS-ASSA2TROVE domain family member 2TROVE2

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