Proteins/UNIPROT:Q93091

RNASE6

ProteinUNIPROT:Q93091

Ribonuclease which shows a preference for the pyrimidines uridine and cytosine. Has potent antibacterial activity against a range of Gram-positive and Gram-negative bacteria, including P.aeruginosa, A.baumanii, M.luteus, S.aureus, E.faecalis, E.faecium, S.saprophyticus and E.coli. Causes loss of bacterial membrane integrity, and also promotes agglutination of Gram-negative bacteria. Probably contributes to urinary tract sterility. Bactericidal activity is independent of RNase activity..

Function from UniProtKB (Q93091), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

10 statements

10 statements · 3 reference databases · Subject: RNASE6 · Sources: Hetionet, Reactome, WikiPathways

Order

RNASE6 covaries with LCE3DProteinHetionet hetionet:covaries:6039-84648Inferred only
OR10R2 covaries with RNASE6ProteinHetionet hetionet:covaries:343406-6039Inferred only
TAS2R14 covaries with RNASE6ProteinHetionet hetionet:covaries:50840-6039Inferred only
RNASE6 covaries with TMEM80ProteinHetionet hetionet:covaries:283232-6039Inferred only
RNASE6 covaries with TTC36ProteinHetionet hetionet:covaries:143941-6039Inferred only
ARR3 interacts with RNASE6ProteinHetionet hetionet:interacts:407-6039Inferred only
RNASE6 participates in Antimicrobial peptidesPathwayReactome R-HSA-6803157Inferred only
RNASE6 participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
RNASE6 participates in Innate Immune SystemPathwayReactome R-HSA-168249Inferred only
RNASE6 participates in TYROBP causal network in microgliaPathwayWikiPathways WP3945Inferred only

Other names

2 names

Resolves to: RNASE6

Also called: RNase K6RNS6

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