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Proteins/UNIPROT:O14921

RGS13

Protein·UNIPROT:O14921

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Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to both G(i)-alpha and G(q)-alpha (By similarity)..

Function from UniProtKB (O14921), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

9 statements

9 statements · 3 reference databases · Subject: RGS13 · Sources: gene ontology, Hetionet, Reactome

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GNAQ interacts with RGS13ProteinHetionet hetionet:interacts:2776-6003Inferred only
PRKACA interacts with RGS13ProteinHetionet hetionet:interacts:5566-6003Inferred only
RGS13 interacts with UBCProteinHetionet hetionet:interacts:6003-7316Inferred only
RGS13 participates in G alpha (i) signalling eventsPathwayReactome R-HSA-418594Inferred only
RGS13 participates in G alpha (q) signalling eventsPathwayReactome R-HSA-416476Inferred only
RGS13 participates in GPCR downstream signallingPathwayReactome R-HSA-388396Inferred only
RGS13 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
RGS13 participates in Signaling by GPCRPathwayReactome R-HSA-372790Inferred only
RGS13 regulates negative regulation of G protein-coupled receptor signaling pathwayBiological processgene ontology O14921|GO:0045744Inferred only

Other names

1 name

Resolves to: RGS13

Also called: Regulator of G protein signaling 13

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