Proteins/UNIPROT:Q6NSI4

RADX

ProteinUNIPROT:Q6NSI4

Single-stranded DNA-binding protein recruited to replication forks to maintain genome stability. Prevents fork collapse by antagonizing the accumulation of RAD51 at forks to ensure the proper balance of fork remodeling and protection without interfering with the capacity of cells to complete homologous recombination of double-strand breaks..

Function from UniProtKB (Q6NSI4), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

8 statements

8 statements · 2 reference databases · Subject: RADX · Sources: gene ontology, Hetionet

Order

RADX covaries with MYH11ProteinHetionet hetionet:covaries:4629-55086Inferred only
RADX covaries with TMEM45BProteinHetionet hetionet:covaries:120224-55086Inferred only
MLH1 interacts with RADXProteinHetionet hetionet:interacts:4292-55086Inferred only
RADX interacts with PLEKHF2ProteinHetionet hetionet:interacts:55086-79666Inferred only
UBC interacts with RADXProteinHetionet hetionet:interacts:55086-7316Inferred only
UBD interacts with RADXProteinHetionet hetionet:interacts:10537-55086Inferred only
RADX regulates negative regulation of double-strand break repair via homologous recombinationBiological processgene ontology Q6NSI4|GO:2000042Inferred only
RADX regulates regulation of DNA repairBiological processgene ontology Q6NSI4|GO:0006282Inferred only

Other names

3 names

Resolves to: RADX

Also called: CXorf57RPA-related and RAD51-antagonist, X-chromosomeRPA-related protein RADX

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