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Proteins/UNIPROT:P25105

PTAFR

Protein·UNIPROT:P25105

Open in the graph

Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system..

Function from UniProtKB (P25105), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

29 statements

29 statements · 3 reference databases · Subject: PTAFR · Sources: Hetionet, Reactome, WikiPathways

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OR4F15 covaries with PTAFRProteinHetionet hetionet:covaries:390649-5724Inferred only
ZNF333 covaries with PTAFRProteinHetionet hetionet:covaries:5724-84449Inferred only
ARR3 interacts with PTAFRProteinHetionet hetionet:interacts:407-5724Inferred only
ARRB2 interacts with PTAFRProteinHetionet hetionet:interacts:409-5724Inferred only
CALM1 interacts with PTAFRProteinHetionet hetionet:interacts:5724-808Inferred only
CALM1 interacts with PTAFRProteinHetionet hetionet:interacts:5724-805Inferred only
CALM1 interacts with PTAFRProteinHetionet hetionet:interacts:5724-801Inferred only
PTAFR interacts with GORABProteinHetionet hetionet:interacts:5724-92344Inferred only
PTAFR interacts with GTPBP3ProteinHetionet hetionet:interacts:5724-84705Inferred only
PTAFR interacts with RGS4ProteinHetionet hetionet:interacts:5724-5999Inferred only
PTAFR interacts with SPATA24ProteinHetionet hetionet:interacts:202051-5724Inferred only
PTAFR interacts with TYK2ProteinHetionet hetionet:interacts:5724-7297Inferred only

Show the remaining 17

PTAFR interacts with UBCProteinHetionet hetionet:interacts:5724-7316Inferred only
PTAFR participates in Class A/1 (Rhodopsin-like receptors)PathwayReactome R-HSA-373076Inferred only
PTAFR participates in Cytokine Signaling in Immune systemPathwayReactome R-HSA-1280215Inferred only
PTAFR participates in G alpha (q) signalling eventsPathwayReactome R-HSA-416476Inferred only
PTAFR participates in GPCR downstream signallingPathwayReactome R-HSA-388396Inferred only
PTAFR participates in GPCR ligand bindingPathwayReactome R-HSA-500792Inferred only
PTAFR participates in GPCRs class A rhodopsin likePathwayWikiPathways WP455Inferred only
PTAFR participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
PTAFR participates in Innate Immune SystemPathwayReactome R-HSA-168249Inferred only
PTAFR participates in Interferon gamma signalingPathwayReactome R-HSA-877300Inferred only
PTAFR participates in Interferon SignalingPathwayReactome R-HSA-913531Inferred only
PTAFR participates in Interleukin-10 signalingPathwayReactome R-HSA-6783783Inferred only
PTAFR participates in Neutrophil degranulationPathwayReactome R-HSA-6798695Inferred only
PTAFR participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
PTAFR participates in Signaling by GPCRPathwayReactome R-HSA-372790Inferred only
PTAFR participates in Signaling by InterleukinsPathwayReactome R-HSA-449147Inferred only
PTAFR participates in Small ligand GPCRsPathwayWikiPathways WP247Inferred only

Other names

2 names

Resolves to: PTAFR

Also called: PAF-RPAFR

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